Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | GMNN | O75496 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | IGF1R | P08069 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8442719 | 0.83 | GAA (0.61) | MAPTTSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8444489 | 0.77 | HTR1A (0.59) | CYP1A2CYP3A4CYP2D6ALOX15LMNA | |
| SCHEMBL8944148 | 0.76 | IGF1R (0.79) | MAPTKMT2AMEN1TSHRCYP1A2 | |
| SCHEMBL2114387 | 0.75 | ADRB1 (0.67) | — | |
| SCHEMBL9258046 | 0.75 | PANK3 (0.51) | MAPTKMT2AMEN1TSHRALOX15 | |
| SCHEMBL368137 | 0.74 | MAPT (0.57) | MAPTKMT2AMEN1TSHRCYP1A2 | |
| SCHEMBL10021750 | 0.74 | HTR1A (0.62) | MAPTKMT2AMEN1TSHRCYP1A2 | |
| Brl-15,572 SCHEMBL7741355 | 0.74 | MEN1 (1.00) | MAPTKMT2AMEN1TSHRCYP1A2 | |
| Brl-15,572 SCHEMBL17978413 | 0.73 | MEN1 (1.00) | MAPTKMT2AMEN1TSHRCYP1A2 | |
| SCHEMBL10052740 | 0.72 | HTR1A (0.64) | MAPTKMT2AMEN1TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340812-A | Antiserotonin. anxiolytic agents | JOHN WYETH & BROTHER, LIMITED (GB) | 1994-08-23 | — | — | US | disclosed |