Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 9/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9305039 | 0.86 | CYP19A1 (0.67) | CYP19A1ALOX15ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL27492176 | 0.82 | PGR (0.61) | IDO1CYP19A1ALDH1A1GFERKDM4E | |
| SCHEMBL28692275 | 0.69 | KMT2A (0.67) | ALDH1A1GAAMEN1KMT2APKM | |
| SCHEMBL8795345 | 0.67 | MAPT (0.61) | IDO1ALOX15ALDH1A1GFERCYP3A4 | |
| SCHEMBL2251010 | 0.67 | KAT6A (0.59) | IDO1CYP19A1ALDH1A1GFERKDM4E | |
| SCHEMBL9301411 | 0.67 | NPC1 (0.50) | HPGDMEN1KMT2A | |
| SCHEMBL27599728 | 0.67 | PNMT (0.50) | IDO1CYP3A4 | |
| SCHEMBL3791521 | 0.66 | PGR (0.81) | CYP19A1ALOX15ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL343776 | 0.66 | HTR6 (0.73) | CYP19A1ALOX15ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL14937571 | 0.66 | PGR (0.72) | CYP19A1ALOX15ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |