Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 9/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302817 | 0.89 | AIMP2 (0.53) | MAPTMAPK1LTA4HHTR1ASIGMAR1 | |
| SCHEMBL9303117 | 0.89 | LTA4H (0.48) | MAPTMAPK1LTA4H | |
| SCHEMBL9301593 | 0.87 | SIGMAR1 (0.48) | MAPTLTA4HHTR1ASIGMAR1DRD4 | |
| SCHEMBL9302778 | 0.87 | SIGMAR1 (0.46) | MAPTMAPK1LTA4HSIGMAR1DRD4 | |
| SCHEMBL9301861 | 0.86 | BACE1 (0.49) | ACHEBACE1BCHECXCR4DRD4 | |
| SCHEMBL9300946 | 0.83 | NPC1 (0.52) | ACHELTA4HSIGMAR1BCHE | |
| SCHEMBL9301877 | 0.83 | BACE1 (0.43) | ACHEBACE1BCHECXCR4DRD4 | |
| SCHEMBL9301653 | 0.82 | ACHE (0.47) | ACHEMAPTMAPK1LTA4HHTR1A | |
| SCHEMBL9302321 | 0.80 | ATM (0.42) | MAPTMAPK1LTA4HSIGMAR1 | |
| SCHEMBL9302303 | 0.78 | EPHX2 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |