Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | GPR6 | P46095 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302452 | 0.90 | KDM4E (0.44) | CXCR4DRD4DRD2DRD3 | |
| SCHEMBL9302546 | 0.88 | SIGMAR1 (0.46) | DRD4CHRM2CHRM3DRD2CHRM1 | |
| SCHEMBL9301121 | 0.83 | ACHE (0.45) | BACE1ACHEBCHECXCR4DRD4 | |
| SCHEMBL9301861 | 0.82 | BACE1 (0.49) | BACE1ACHEBCHECXCR4DRD4 | |
| SCHEMBL9301885 | 0.76 | CXCR4 (0.56) | BACE1ACHECXCR4DRD4MEN1 | |
| SCHEMBL9301438 | 0.75 | ACHE (0.51) | BACE1ACHEBCHECXCR4DRD4 | |
| SCHEMBL9302484 | 0.74 | NISCH (0.39) | MEN1KMT2A | |
| SCHEMBL9302817 | 0.73 | AIMP2 (0.53) | CXCR4DRD4DRD2DRD3 | |
| SCHEMBL9303169 | 0.72 | ACHE (0.47) | BACE1ACHEBCHECXCR4DRD4 | |
| SCHEMBL9303117 | 0.72 | LTA4H (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |