SCHEMBL9301484

SCHEMBL9301484

O=P(O)(O)C(N1CCC(O)CC1)P(=O)(O)O

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FDPS P14324 3/20 0.58
GPR119 Q8TDV5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL762417 0.80 FDPS (0.56) FDPS
SCHEMBL203348 0.80 FDPS (0.75) FDPS
SCHEMBL3080928 0.80 FDPS (0.75) FDPS
SCHEMBL898693 0.80 FDPS (0.75) FDPS
SCHEMBL9301817 0.79 FDPS (0.38) FDPS
SCHEMBL2203676 0.75 FDPS (0.85) FDPS
SCHEMBL9302016 0.74 FDPS (0.64) FDPS
SCHEMBL2472093 0.73 FDPS (1.00) FDPS
N-(Hexamethyleneimino)Methylenebisphosphonic Acid SCHEMBL12309768 0.73 FDPS (1.00) FDPS
SCHEMBL9356971 0.71 FDPS (0.62) FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220389191-A1 POLYMER COMPOSITION COMPRISING PHOSPHONATE FLAME RETARDANT CHEMISCHE FABRIK BUDENHEIM KG (DE) 2022-12-08 US disclosed
WO-2021028496-A1 POLYMER COMPOSITION COMPRISING PHOSPHONATE FLAME RETARDANT CHEMISCHE FABRIK BUDENHEIM KG (DE) 2021-02-18 WO disclosed
US-5350743-A Treatment of osteoporosis KAKEN PHARMACEUTICAL CO., LTD. (JP) 1994-09-27 US disclosed
EP-0498424-A1 Bisphosphonic acid derivatives and bone resorption inhibitors containing them Kaken Pharmaceutical Co., Ltd. (JP) 1992-08-12 EP disclosed