Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.64 |
| ▸ | L3MBTL3 | Q96JM7 | 11/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 10/20 | 0.41 |
| ▸ | MBTD1 | Q05BQ5 | 5/20 | 0.41 |
| ▸ | TP53BP1 | Q12888 | 2/20 | 0.39 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301764 | 0.82 | FDPS (0.44) | FDPSL3MBTL3L3MBTL1MBTD1MEN1 | |
| SCHEMBL2472093 | 0.80 | FDPS (1.00) | FDPSMEN1ALDH1A1KMT2A | |
| N-(Hexamethyleneimino)Methylenebisphosphonic Acid SCHEMBL12309768 | 0.80 | FDPS (1.00) | FDPSMEN1ALDH1A1KMT2A | |
| SCHEMBL14403096 | 0.74 | L3MBTL3 (0.47) | L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL9301484 | 0.74 | FDPS (0.58) | FDPS | |
| SCHEMBL2203676 | 0.73 | FDPS (0.85) | FDPS | |
| SCHEMBL762417 | 0.72 | FDPS (0.56) | FDPSMEN1ALDH1A1KMT2A | |
| SCHEMBL203348 | 0.72 | FDPS (0.75) | FDPSKDM4E | |
| SCHEMBL898693 | 0.72 | FDPS (0.75) | FDPSKDM4E | |
| SCHEMBL3080928 | 0.72 | FDPS (0.75) | FDPSKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350743-A | Treatment of osteoporosis | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1994-09-27 | — | — | US | disclosed |
| EP-0498424-A1 | Bisphosphonic acid derivatives and bone resorption inhibitors containing them | Kaken Pharmaceutical Co., Ltd. (JP) | 1992-08-12 | — | — | EP | disclosed |