Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.61 |
| ▸ | AGER | Q15109 | 3/20 | 0.58 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CCR5 | P51681 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13434090 | 0.92 | L3MBTL1 (0.51) | L3MBTL1HSD11B1AGERMTNR1AALDH1A1 | |
| SCHEMBL10722280 | 0.92 | HSD11B1 (0.70) | L3MBTL1HSD11B1AGERMTNR1AMEN1 | |
| SCHEMBL10720234 | 0.89 | HSD11B1 (0.56) | L3MBTL1HSD11B1AGERMTNR1AALDH1A1 | |
| SCHEMBL13911269 | 0.88 | AGER (0.56) | L3MBTL1HSD11B1AGERMTNR1ASLC6A4 | |
| SCHEMBL1353088 | 0.86 | LMNA (0.65) | L3MBTL1HSD11B1AGERMTNR1AMEN1 | |
| SCHEMBL10720319 | 0.85 | L3MBTL1 (0.60) | L3MBTL1HSD11B1SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL9001746 | 0.85 | HSD11B1 (0.54) | L3MBTL1HSD11B1AGERMTNR1ASLC6A4 | |
| SCHEMBL5599731 | 0.84 | HSD11B1 (0.46) | L3MBTL1HSD11B1AGERMTNR1AALDH1A1 | |
| SCHEMBL4634860 | 0.84 | SLC6A4 (0.57) | L3MBTL1HSD11B1SLC6A2SLC6A4 | |
| SCHEMBL96038 | 0.84 | HSD11B1 (0.62) | L3MBTL1HSD11B1AGERMTNR1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101962384-A | Chromene compounds, a process for their preparation and pharmaceutical compositions containing them | SERVIER LAB | 2011-02-02 | — | — | CN | claimed |
| CN-102365280-B | adenosine receptor ligands and uses thereof | DOMAIN THERAPEUTICS (FR) | 2014-10-29 | — | — | CN | disclosed |
| CN-101962384-B | Chromene compounds, a process for their preparation and pharmaceutical compositions containing them | SERVIER LAB | 2013-04-10 | — | — | CN | disclosed |
| CN-101962384-A | Chromene compounds, a process for their preparation and pharmaceutical compositions containing them | SERVIER LAB | 2011-02-02 | — | — | CN | disclosed |
| EP-2021004-A2 | SUBSTITUTED AZASPIRO DERIVATIVES | NEUROGEN CORPORATION (US) | 2009-02-11 | — | — | EP | disclosed |
| WO-2007133561-A2 | SUBSTITUTED AZASPIRO DERIVATIVES | NEUROGEN CORPORATION (US) | 2007-11-22 | — | — | WO | disclosed |
| EP-1740584-A1 | FUSED QUINOLINE DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005105802-A1 | FUSED QUINOLINE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-11-10 | — | — | WO | disclosed |