SCHEMBL9301702

SCHEMBL9301702

CCCCOCn1c(-c2ccc(Cl)cc2)c(C#N)c(Br)c1C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.33
ALDH1A1 P00352 3/20 0.33
LMNA P02545 3/20 0.33
HPGD P15428 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
RXFP1 Q9HBX9 1/20 0.32
GRIA2 P42262 1/20 0.32
GRIA4 P48058 1/20 0.32
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
GLA P06280 1/20 0.32
GAA P10253 1/20 0.32
CRHBP P24387 1/20 0.32
HTT P42858 1/20 0.32
CRHR2 Q13324 1/20 0.32
MAPT P10636 1/20 0.32
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorfenapyr SCHEMBL40337 0.90 RXFP1 (0.35) KDM4EALDH1A1LMNAHPGDRXFP1
Chlorfenapyr SCHEMBL28530561 0.89 RXFP1 (0.35) KDM4EALDH1A1LMNAHPGDRXFP1
Chlorfenapyr SCHEMBL27488880 0.89 RXFP1 (0.35) KDM4EALDH1A1LMNAHPGDRXFP1
Chlorfenapyr SCHEMBL28508419 0.88 RXFP1 (0.36) KDM4EALDH1A1LMNAHPGDRXFP1
SCHEMBL27916628 0.88 KDM4E (0.33) KDM4EALDH1A1LMNAHPGDMEN1
SCHEMBL5819212 0.85 KDM4E (0.34) KDM4EALDH1A1LMNAHPGDRXFP1
SCHEMBL8428345 0.84 APOBEC3G (0.34) KDM4EALDH1A1LMNAHPGDRXFP1
Chlorfenapyr SCHEMBL28402415 0.84 RXFP1 (0.32) KDM4EALDH1A1HPGDRXFP1GRIA2
Chlorfenapyr SCHEMBL16446552 0.83 MEN1 (0.35) KDM4EALDH1A1HPGDRXFP1GRIA2
Chlorfenapyr SCHEMBL28649822 0.82 GRIA2 (0.37) KDM4EALDH1A1LMNAHPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5359090-A Reacting 1-H-pyrrole compound with dialkoxymethane in presence of vilsmeier reagent and a tertiary amine; useful as pesticidal, insecticidal, fungicidal, bactericidal, miticidal nematocidal and molluscicidal AMERICAN CYANAMID COMPANY (US) 1994-10-25 US disclosed