SCHEMBL27916628

SCHEMBL27916628

N#Cc1c(Br)c(C(F)(F)F)n(COCCCl)c1-c1ccc(Cl)cc1

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
GLA P06280 1/20 0.33
GAA P10253 1/20 0.33
HPGD P15428 1/20 0.33
CRHBP P24387 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
CRHR2 Q13324 1/20 0.33
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorfenapyr SCHEMBL40337 0.89 RXFP1 (0.35) KDM4EMEN1ALDH1A1LMNAGLA
SCHEMBL9301702 0.88 KDM4E (0.33) KDM4EMEN1ALDH1A1LMNAGLA
Chlorfenapyr SCHEMBL27488880 0.88 RXFP1 (0.35) KDM4EMEN1ALDH1A1LMNAGLA
Chlorfenapyr SCHEMBL28530561 0.88 RXFP1 (0.35) KDM4EMEN1ALDH1A1LMNAGLA
Chlorfenapyr SCHEMBL28508419 0.87 RXFP1 (0.36) KDM4EMEN1ALDH1A1LMNAGLA
SCHEMBL5819212 0.86 KDM4E (0.34) KDM4EMEN1ALDH1A1LMNAGLA
SCHEMBL7508068 0.86 KDM4E (0.37) KDM4EMEN1ALDH1A1LMNAGLA
SCHEMBL7499361 0.83 KDM4E (0.37) KDM4EMEN1ALDH1A1LMNAGLA
Chlorfenapyr SCHEMBL28402415 0.82 RXFP1 (0.32) KDM4EALDH1A1HPGD
SCHEMBL8428345 0.82 APOBEC3G (0.34) KDM4EMEN1ALDH1A1LMNAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036637-A Polymorphs 先正达农作物保护股份公司 2026-05-15 CN disclosed
US-12538924-B2 Pesticidally active heterocyclic derivatives with sulfur containing substituents SYNGENTA CROP PROTECTION AG (CH) 2026-02-03 US disclosed
US-12528788-B2 Pesticidally active benzene- and azine-amide compounds SYNGENTA CROP PROTECTION AG (CH) 2026-01-20 US disclosed
EP-3802542-B1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS SYNGENTA CROP PROTECTION AG (CH) 2025-05-28 EP disclosed
CN-113811532-B Pesticidally active heterocyclic derivatives with sulfur containing substituents 先正达农作物保护股份公司 2025-04-11 CN disclosed
CN-119431377-A Pesticidally active heterocyclic derivatives with sulfoximine containing substituents 先正达农作物保护股份公司 2025-02-14 CN disclosed
EP-4480542-A2 NOVEL CRYSTALLINE FORMS Syngenta Crop Protection AG (CH) 2024-12-25 EP disclosed
US-12172999-B2 Polymorphs SYNGENTA CROP PROTECTION AG (CH) 2024-12-24 US disclosed
CN-112839933-B Pesticidally active benzene-amide and azine-amide compounds 先正达参股股份有限公司 2024-12-13 CN disclosed
US-12134614-B2 Polymorphs SYNGENTA CROP PROTECTION AG (CH) 2024-11-05 US disclosed
US-11399542-B2 Pesticidally active heterocyclic derivatives with sulfur containing substituents SYNGENTA PARTICIPATIONS AG (CH) 2022-08-02 US disclosed
US-20220144799-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA CROP PROTECTION AG (CH) 2022-05-12 US disclosed
US-20220132850-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA CROP PROTECTION AG (CH) 2022-05-05 US disclosed
US-20220132852-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA CROP PROTECTION AG (CH) 2022-05-05 US disclosed
CN-109476629-B Urea and thiourea substituted bicyclic derivatives as pesticides 先正达参股股份有限公司 2022-04-15 CN disclosed
EP-3585770-B1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2022-03-23 EP disclosed
US-20220061324-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA CROP PROTECTION AG (CH) 2022-03-03 US disclosed
EP-3621965-B1 IMIDAZOPYRIMIDINE DERIVATIVES WITH SULFUR CONTAINING PHENYL AND PYRIDYL SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2022-02-23 EP disclosed
US-20220048873-A1 PESTICIDALLY ACTIVE CYCLOPROPYL METHYL AMIDE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2022-02-17 US disclosed
CN-103004769-A Acaricidal composition containing chlorine chlorfenapyr and spirodiclofen HUNAN HAILI CHEMICAL INDUSTRY CO LTD 2013-04-03 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12538924-B2 Pesticidally active heterocyclic derivatives with sulfur containing substituents CBR3, CBR1, CYCS KDM4E 1249/4885MEN1 3824/4885ALDH1A1 381/4885
US-12528788-B2 Pesticidally active benzene- and azine-amide compounds CBR3, CBR1, DDT KDM4E 895/4885MEN1 2786/4885ALDH1A1 1002/4885
US-20220132852-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS DDT, ACHE, AADAC KDM4E 1927/4885MEN1 1608/4885ALDH1A1 108/4885
US-11399542-B2 Pesticidally active heterocyclic derivatives with sulfur containing substituents DDT, CHRM1, ACHE KDM4E 3825/4885MEN1 937/4885ALDH1A1 1130/4885
US-12134614-B2 Polymorphs CYP3A43, CYP4F2, CYP1B1 KDM4E 3321/4885MEN1 2761/4885ALDH1A1 209/4885
US-20220061324-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS DDT, ACHE, AADAC KDM4E 2316/4885MEN1 1418/4885ALDH1A1 71/4885
US-12172999-B2 Polymorphs CYP3A43, CYP4F2, CYP1A2 KDM4E 3513/4885MEN1 2449/4885ALDH1A1 216/4885
US-20220048873-A1 PESTICIDALLY ACTIVE CYCLOPROPYL METHYL AMIDE DERIVATIVES ACHE, PNMT, DDT KDM4E 1247/4885MEN1 2176/4885ALDH1A1 664/4885
US-20220144799-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS ACHE, DDT, AADAC KDM4E 1666/4885MEN1 1900/4885ALDH1A1 102/4885
US-20220132850-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS DDT, AADAC, ACHE KDM4E 2168/4885MEN1 752/4885ALDH1A1 127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.