Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.53 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.41 |
| ▸ | FDPS | P14324 | 7/20 | 0.41 |
| ▸ | LAP3 | P28838 | 2/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302434 | 0.80 | FDPS (0.48) | OPRM1OPRD1OPRK1OPRL1S1PR1 | |
| SCHEMBL17607279 | 0.72 | OPRM1 (0.49) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL17731291 | 0.72 | OPRM1 (0.49) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL17730835 | 0.72 | OPRM1 (0.49) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL17607210 | 0.72 | OPRM1 (0.49) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL1868334 | 0.72 | OPRM1 (0.49) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL9303011 | 0.71 | FDPS (0.54) | FDPS | |
| SCHEMBL4437885 | 0.70 | — | — | |
| SCHEMBL5823742 | 0.70 | OPRM1 (0.47) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL4782236 | 0.69 | OPRM1 (0.49) | OPRM1OPRD1OPRK1OPRL1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350743-A | Treatment of osteoporosis | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1994-09-27 | — | — | US | disclosed |
| EP-0498424-A1 | Bisphosphonic acid derivatives and bone resorption inhibitors containing them | Kaken Pharmaceutical Co., Ltd. (JP) | 1992-08-12 | — | — | EP | disclosed |