Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4275635 | 0.81 | PKLR (0.36) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL21840110 | 0.79 | CYP46A1 (0.40) | OPRM1L3MBTL1KMT2AALDH1A1TSHR | |
| SCHEMBL4836593 | 0.78 | GPR4 (0.45) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL238639 | 0.77 | PKLR (0.34) | ALDH1A1 | |
| SCHEMBL5911872 | 0.76 | L3MBTL1 (0.49) | OPRM1OPRD1OPRK1OPRL1L3MBTL1 | |
| SCHEMBL4437885 | 0.76 | — | — | |
| SCHEMBL2141413 | 0.76 | AVPR1A (0.31) | ALDH1A1 | |
| Bicarbonate SCHEMBL8472938 | 0.76 | OPRM1 (0.42) | OPRM1OPRD1OPRK1OPRL1L3MBTL1 | |
| SCHEMBL8048581 | 0.74 | S1PR1 (0.54) | OPRM1OPRD1OPRK1OPRL1CCR1 | |
| SCHEMBL28026857 | 0.74 | KMT2A (0.37) | OPRM1OPRD1OPRK1OPRL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008012623-A1 | BENZIMIDAZOLYL COMPOUNDS AS POTENTIATORS OF MGLUR2 SUBTYPE OF GLUTAMATE RECEPTOR | PFIZER PRODUCTS INC. (US) | 2008-01-31 | — | — | WO | disclosed |