Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7541791 | 0.74 | L3MBTL1 (0.39) | LTA4HSMN1; SMN2ALDH1A1 | |
| SCHEMBL8346336 | 0.72 | CHRM2 (0.36) | ABCB1LTA4HSMN1; SMN2KMT2ASLC15A1 | |
| SCHEMBL28006164 | 0.71 | KCNN4 (0.47) | LTA4HMEN1KMT2AMAPT | |
| SCHEMBL11698202 | 0.70 | LTA4H (0.40) | ABCB1LTA4HSMN1; SMN2MEN1KMT2A | |
| SCHEMBL169622 | 0.70 | LTA4H (0.54) | LTA4HSMN1; SMN2MEN1KMT2ASLC15A1 | |
| SCHEMBL27873595 | 0.70 | LTA4H (0.54) | LTA4HSMN1; SMN2MEN1KMT2ASLC15A1 | |
| SCHEMBL304415 | 0.70 | LTA4H (0.54) | LTA4HSMN1; SMN2MEN1KMT2ASLC15A1 | |
| SCHEMBL11244478 | 0.69 | SLC15A1 (0.39) | ABCB1LTA4HSMN1; SMN2SLC15A1ALDH1A1 | |
| SCHEMBL6904576 | 0.69 | ABCB1 (0.47) | ABCB1LTA4HSLC15A1ALDH1A1CTRB1 | |
| SCHEMBL9330125 | 0.69 | ABCB1 (0.47) | ABCB1LTA4HSLC15A1ALDH1A1CTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5302743-A | Reacting N-protected L-aspartic anhydride with L-phenylalanine methyl ester salt in non-aqueous solvent | MITSUI TOATSU CHEMICALS, INC. (JP) | 1994-04-12 | — | — | US | disclosed |