Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 2/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301965 | 0.85 | BTK (0.43) | TGM2ELANEEPHX2CYP3A4BTK | |
| SCHEMBL9183678 | 0.81 | ELANE (0.50) | ELANEKDM1AGAANPC1RAB9A | |
| SCHEMBL4743993 | 0.78 | TGM2 (0.63) | TGM2GAANPC1RAB9AEPHX2 | |
| SCHEMBL4143696 | 0.78 | ELANE (0.64) | ELANEKDM1ATHRBRAB9AMEN1 | |
| SCHEMBL732934 | 0.77 | TGM2 (0.81) | TGM2MEN1KMT2ALMNA | |
| SCHEMBL5479758 | 0.77 | PPARA (0.57) | TGM2MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL4137908 | 0.77 | ELANE (0.51) | ELANEKDM1ATHRBMAPKAPK2 | |
| SCHEMBL1866948 | 0.76 | HPGD (0.40) | TGM2THRBGAANPC1RAB9A | |
| SCHEMBL196293 | 0.76 | ELANE (0.66) | ELANEKDM1AMEN1KMT2AMAPKAPK2 | |
| SCHEMBL8476285 | 0.76 | MEN1 (0.60) | TGM2NPC1RAB9AEPHX2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326840-A | Radiation-sensitive mixture containing novel polymers embodying units composed of amides of α, β-unsaturated carboxylic acids as binders | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-07-05 | — | — | US | disclosed |