SCHEMBL930208

SCHEMBL930208

Cc1cccc(C2CC2)c1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
HTR2C P28335 6/20 0.48
TRPA1 O75762 2/20 0.48
GABRA1 P14867 1/20 0.42
GABRB2 P47870 1/20 0.42
HPGD P15428 2/20 0.41
KDM4E B2RXH2 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MAP3K14 Q99558 1/20 0.39
ATM Q13315 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
CYP2C19 P33261 1/20 0.38
OPRL1 P41146 1/20 0.38
KCNH2 Q12809 1/20 0.38
NOTUM Q6P988 1/20 0.37
TAS1R3 Q7RTX0 1/20 0.36
TAS1R1 Q7RTX1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL466853 0.92 ALDH1A1 (0.50) ALDH1A1HTR2CTRPA1GABRA1GABRB2
SCHEMBL673222 0.90 ALDH1A1 (0.48) ALDH1A1HTR2CTRPA1GABRA1GABRB2
SCHEMBL30218222 0.90 ALDH1A1 (0.48) ALDH1A1HTR2CTRPA1GABRA1GABRB2
SCHEMBL8954630 0.90 ALDH1A1 (0.48) ALDH1A1HTR2CTRPA1GABRA1GABRB2
Methane SCHEMBL9104929 0.88 ALDH1A1 (0.46) ALDH1A1HTR2CTRPA1GABRA1GABRB2
SCHEMBL2048750 0.84 NOTUM (0.38) ALDH1A1HTR2CHPGDHSD17B10NOTUM
SCHEMBL21884033 0.82 ALDH1A1 (0.48) ALDH1A1HTR2CTRPA1GABRA1GABRB2
SCHEMBL16958457 0.80 HTR2C (0.50) ALDH1A1HTR2CMAP3K14OPRL1KCNH2
SCHEMBL15517656 0.80 ALDH1A1 (0.42) ALDH1A1HTR2CTRPA1GABRA1GABRB2
SCHEMBL2049409 0.78 HTR2C (0.44) ALDH1A1HTR2CTRPA1KDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7964531-B2 3-phenoxy-4-pyridazinol derivatives and herbicidal composition containing the same MITSUI CHEMICALS AGRO, INC. (JP) 2011-06-21 US claimed
US-20100041555-A1 3-Phenoxy-4-pyridazinol derivatives and herbicidal composition containing the same MITSUI CHEMICALS AGRO, INC. (JP) 2010-02-18 US claimed
CN-101541859-A Poly (arylene ether) copolymer SABIC INNOVATIVE PLASTICS IP (NL) 2009-09-23 CN claimed
US-20080076884-A1 POLY(ARYLENE ETHER) COMPOSITION AND METHOD CITIBANK, N.A., AS COLLATERAL AGENT 2008-03-27 US claimed
US-20050037925-A1 3-phenoxy-4-pyridazinol derivatives and herbicide composition containing the same SANKYO AGRO COMPANY, LIMITED (JP) 2005-02-17 US claimed
CN-121975880-A Cycloxazin ester, green continuous synthesis method thereof and application thereof in herbicide 上海群力化工有限公司 2026-05-05 CN disclosed
US-20250340574-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR VERTEX PHARMA (US) 2025-11-06 US disclosed
CN-120682086-A Safe preparation process of 2-cyclopropyl-6-methylphenol 武汉工程大学 2025-09-23 CN disclosed
CN-120682086-A Safe preparation process of 2-cyclopropyl-6-methylphenol 武汉工程大学 2025-09-23 CN disclosed
EP-4504739-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR Vertex Pharmaceuticals Incorporated (US) 2025-02-12 EP disclosed
CN-113788741-B Method for preparing 2-cyclopropyl phenol derivative 大连九信精细化工有限公司 2023-12-29 CN disclosed
US-20230374038-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR VERTEX PHARMACEUTICALS (SAN DIEGO) LLC 2023-11-23 US disclosed
WO-2008036454-A1 POLY (ARYLENE ETHER) COPOLYMER SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-03-27 WO disclosed
US-20080076885-A1 POLY(ARYLENE ETHER) COMPOSITION AND METHOD CITIBANK, N.A., AS COLLATERAL AGENT 2008-03-27 US disclosed
US-20080076884-A1 POLY(ARYLENE ETHER) COMPOSITION AND METHOD CITIBANK, N.A., AS COLLATERAL AGENT 2008-03-27 US disclosed
CN-101151234-A Process for producing cyclopropylphenol derivative SANKYO AGRO CO LTD (JP) 2008-03-26 CN disclosed
EP-1880987-A1 PROCESS FOR PRODUCING CYCLOPROPYLPHENOL DERIVATIVE Sankyo Agro Company, Limited (JP) 2008-01-23 EP disclosed
US-20050037925-A1 3-phenoxy-4-pyridazinol derivatives and herbicide composition containing the same SANKYO AGRO COMPANY, LIMITED (JP) 2005-02-17 US disclosed
CN-1543455-A 3-phenoxy-4-pyridazinol derivatives and herbicidal compositions containing the same 三共农业株式会社 2004-11-03 CN disclosed
EP-1426365-A1 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME Sankyo Agro Company, Limited (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230374038-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR CFTR, SCNN1G, SCNN1B ALDH1A1 4121/4885HTR2C 4356/4885TRPA1 272/4885
US-20250340574-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR CFTR, SCNN1G, SCNN1B ALDH1A1 3983/4885HTR2C 4427/4885TRPA1 262/4885
US-20100041555-A1 3-Phenoxy-4-pyridazinol derivatives and herbicidal composition containing the same CBR3, DDT, CBR1 ALDH1A1 447/4885HTR2C 434/4885TRPA1 700/4885
US-20050037925-A1 3-phenoxy-4-pyridazinol derivatives and herbicide composition containing the same CBR3, DDT, CHRM2 ALDH1A1 762/4885HTR2C 634/4885TRPA1 752/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.