Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 7/20 | 0.37 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15517656 | 0.86 | ALDH1A1 (0.42) | ALDH1A1TRPA1GABRA1GABRB2HPGD | |
| SCHEMBL930208 | 0.82 | ALDH1A1 (0.54) | ALDH1A1TRPA1GABRA1GABRB2HPGD | |
| SCHEMBL17297901 | 0.79 | HTR2C (0.53) | ALDH1A1HTR2CHTR2AHTR2BTAAR1 | |
| SCHEMBL466853 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TRPA1GABRA1GABRB2HPGD | |
| SCHEMBL8954630 | 0.77 | ALDH1A1 (0.48) | ALDH1A1TRPA1GABRA1GABRB2HTR2C | |
| SCHEMBL18512269 | 0.77 | KDM1A (0.34) | HTR2CHTR2AHTR2B | |
| SCHEMBL673222 | 0.77 | ALDH1A1 (0.48) | ALDH1A1TRPA1GABRA1GABRB2HTR2C | |
| SCHEMBL30218222 | 0.77 | ALDH1A1 (0.48) | ALDH1A1TRPA1GABRA1GABRB2HTR2C | |
| SCHEMBL22096912 | 0.77 | CA2 (0.53) | ALDH1A1GABRA1GABRB2ATM | |
| SCHEMBL19769063 | 0.77 | GABRA1 (0.53) | ALDH1A1GABRA1GABRB2HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10597377-B2 | Somatostatin modulators and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2020-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10597377-B2 | Somatostatin modulators and uses thereof | SSTR5, SSTR2, SSTR4 | ALDH1A1 4626/4885TRPA1 1736/4885GABRA1 322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.