Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | DDX3X | O00571 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | EDNRA | P25101 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20549152 | 0.84 | MAPT (0.71) | MAPTALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL7079113 | 0.81 | ALDH1A1 (0.74) | MAPTALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL19332655 | 0.79 | KDM4E (0.49) | MAPTALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL29227834 | 0.78 | MAPT (0.65) | MAPTALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL19332591 | 0.78 | L3MBTL1 (0.50) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL30939451 | 0.78 | MAPT (0.65) | MAPTALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL1094138 | 0.77 | POLB (0.55) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL6292016 | 0.76 | SLC40A1 (0.55) | KMT2ACA2MEN1EDNRAGAA | |
| SCHEMBL17978504 | 0.76 | ALDH1A1 (0.70) | MAPTALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL30939468 | 0.76 | MAPT (0.59) | MAPTALDH1A1KDM4ELMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5360802-A | Antagonists of cholecystokinin and gastrin | MERCK SHARPE & DOHME LTD. | 1994-11-01 | — | — | US | disclosed |
| EP-0514133-A1 | Benzodiazepine derivatives, compositions containing them and their use in therapy | MERCK SHARP & DOHME LTD. (GB) | 1992-11-19 | — | — | EP | disclosed |