Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302896 | 0.92 | HSP90AA1 (0.46) | PTGS2ALDH1A1KDM4EPOLBGAA | |
| SCHEMBL9182334 | 0.79 | KMT2A (0.48) | PTGS2ALDH1A1KDM4EPOLBGAA | |
| SCHEMBL28982768 | 0.77 | KDM4E (0.63) | PTGS2ALDH1A1KDM4EPOLBGAA | |
| SCHEMBL9806551 | 0.73 | PDK2 (0.70) | ALDH1A1KDM4EPOLBGAATDP1 | |
| SCHEMBL9410533 | 0.73 | PTGS2 (0.40) | PTGS2ALDH1A1KDM4EPOLBGAA | |
| SCHEMBL28219703 | 0.72 | ALDH1A1 (0.50) | PTGS2ALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL9410532 | 0.72 | SMAD3 (0.59) | — | |
| SCHEMBL9185831 | 0.72 | MEN1 (0.49) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL4659413 | 0.70 | MEN1 (0.67) | ALDH1A1KDM4EPOLBGAATDP1 | |
| SCHEMBL11097088 | 0.69 | GAA (0.73) | ALDH1A1KDM4EPOLBGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310913-A | Immunomodulators | KABI PHARMACIA AKTIEBOLAG (SE) | 1994-05-10 | — | — | US | claimed |