Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302285 | 0.92 | PTGS2 (0.47) | HSP90AA1PDK2PDK1PDK3PDK4 | |
| SCHEMBL9184851 | 0.77 | KDM5A (0.45) | HSP90AA1PDK2PDK1PDK3PDK4 | |
| SCHEMBL28982768 | 0.76 | KDM4E (0.63) | GAAALDH1A1KDM4EHPGDGLA | |
| SCHEMBL11097088 | 0.71 | GAA (0.73) | GAAALDH1A1KDM4EHPGDGLA | |
| SCHEMBL9182334 | 0.70 | KMT2A (0.48) | GAAALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL2054592 | 0.69 | KIF11 (0.44) | GAAALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL9182411 | 0.67 | KDM4E (0.52) | GAAALDH1A1KDM4EPOLBTDP1 | |
| SCHEMBL12550506 | 0.66 | HSP90AA1 (0.47) | HSP90AA1PDK2PDK1PDK3PDK4 | |
| SCHEMBL2272356 | 0.66 | AR (0.62) | GAAALDH1A1KDM4EHPGDPKM | |
| SCHEMBL6802143 | 0.65 | HSP90AA1 (0.60) | HSP90AA1PDK2PDK1PDK3PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310913-A | Immunomodulators | KABI PHARMACIA AKTIEBOLAG (SE) | 1994-05-10 | — | — | US | claimed |