Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303300 | 0.91 | L3MBTL1 (0.70) | L3MBTL1KDM4EMEN1KMT2ADRD4 | |
| SCHEMBL10379764 | 0.88 | L3MBTL1 (0.62) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL9302315 | 0.86 | KDM4E (0.51) | L3MBTL1MAPK1KDM4EPOLBMEN1 | |
| SCHEMBL9193205 | 0.85 | L3MBTL1 (0.59) | L3MBTL1KDM4EMEN1KMT2AGLA | |
| SCHEMBL9187274 | 0.85 | MAPT (0.60) | L3MBTL1KDM4EMEN1KMT2AGLA | |
| SCHEMBL9192429 | 0.85 | KCNH2 (0.64) | L3MBTL1MAPK1KDM4EKMT2ADRD4 | |
| SCHEMBL9302848 | 0.83 | L3MBTL1 (0.74) | L3MBTL1KDM4EMEN1KMT2ADRD4 | |
| SCHEMBL9301602 | 0.83 | TSHR (0.64) | KDM4EMEN1KMT2AGLAMAPT | |
| SCHEMBL9300891 | 0.83 | TSHR (0.64) | KDM4EMEN1KMT2AGLAMAPT | |
| SCHEMBL9301397 | 0.82 | MAPT (0.57) | L3MBTL1KDM4EMEN1KMT2AGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5342839-A | Useful for therapy of oxygen deficiency diseases of the brain | BASF AKTIENGESELLSCHAFT (DE) | 1994-08-30 | — | — | US | disclosed |