Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | DRD4 | P21917 | 4/20 | 0.59 |
| ▸ | DRD2 | P14416 | 3/20 | 0.59 |
| ▸ | DRD3 | P35462 | 3/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303300 | 0.92 | L3MBTL1 (0.70) | L3MBTL1MEN1KMT2AKDM4ECYP2D6 | |
| SCHEMBL9301892 | 0.91 | KMT2A (0.67) | L3MBTL1MEN1KMT2AKDM4ECYP2D6 | |
| SCHEMBL4577971 | 0.87 | L3MBTL1 (0.97) | L3MBTL1MEN1KMT2AKDM4ECYP2D6 | |
| SCHEMBL11240406 | 0.87 | L3MBTL1 (0.97) | L3MBTL1MEN1KMT2AKDM4ECYP2D6 | |
| SCHEMBL3970369 | 0.87 | L3MBTL1 (0.97) | L3MBTL1MEN1KMT2AKDM4ECYP2D6 | |
| SCHEMBL10379764 | 0.84 | L3MBTL1 (0.62) | L3MBTL1MEN1KMT2AKDM4ECYP2D6 | |
| SCHEMBL9193205 | 0.84 | L3MBTL1 (0.59) | L3MBTL1MEN1KMT2AKDM4ECYP2D6 | |
| SCHEMBL9302474 | 0.83 | L3MBTL1 (0.64) | L3MBTL1MEN1KMT2AKDM4ECYP2D6 | |
| SCHEMBL6131254 | 0.83 | KDM4E (0.85) | L3MBTL1MEN1KMT2AKDM4ECYP2D6 | |
| SCHEMBL25010831 | 0.81 | KDM4E (1.00) | L3MBTL1MEN1KMT2AKDM4ECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5342839-A | Useful for therapy of oxygen deficiency diseases of the brain | BASF AKTIENGESELLSCHAFT (DE) | 1994-08-30 | — | — | US | disclosed |
| EP-0435902-A1 | 2-HYDROXY-3-PHENOXY-PROPYL-SUBSTITUTED PIPERAZINES AND HOMOPIPERAZINES, THEIR MANUFACTURE AND USE. | BASF AG (DE) | 1991-07-10 | — | — | EP | disclosed |
| WO-1990003371-A1 | 2-HYDROXY-3-PHENOXY-PROPYL-SUBSTITUTED PIPERAZINES AND HOMOPIPERAZINES, THEIR MANUFACTURE AND USE | BASF AKTIENGESELLSCHAFT (DE) | 1990-04-05 | — | — | WO | disclosed |