Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303262 | 1.00 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2TP53LMNAHTT | |
| SCHEMBL11163798 | 0.81 | FFAR3 (0.36) | ALDH1A1TP53LTA4H | |
| SCHEMBL14753764 | 0.81 | FFAR3 (0.36) | ALDH1A1TP53LTA4H | |
| SCHEMBL11732733 | 0.78 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2TP53LMNAHTT | |
| SCHEMBL11732740 | 0.78 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2TP53LMNAHTT | |
| SCHEMBL226149 | 0.78 | — | — | |
| SCHEMBL8990012 | 0.77 | TSHR (0.33) | ALDH1A1TP53TSHRLTA4H | |
| SCHEMBL17814865 | 0.77 | LTA4H (0.36) | TP53LTA4H | |
| SCHEMBL11166642 | 0.77 | LTA4H (0.40) | ALDH1A1TP53LTA4H | |
| SCHEMBL11156860 | 0.75 | TP53 (0.38) | TP53LTA4HSLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5348882-A | Preparation of intermediates for cyclosporins and cyclic peptides for antibiotic and immunosuppressive action in tissue transplants | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1994-09-20 | — | — | US | disclosed |
| EP-0514780-A2 | Process for the preparation of linear enantiomer-pure N-alkyl-L or D-amino acids | Degussa Aktiengesellschaft (DE) | 1992-11-25 | — | — | EP | disclosed |