Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.59 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.56 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL230157 | 0.83 | POLB (0.84) | POLBNPC1RAB9ACHRM1DDAH1 | |
| SCHEMBL833457 | 0.83 | POLB (0.66) | POLBNPC1RAB9ACHRM1DDAH1 | |
| SCHEMBL8322003 | 0.83 | POLB (0.66) | POLBNPC1RAB9ACHRM1DDAH1 | |
| SCHEMBL28799253 | 0.82 | DDAH1 (0.59) | POLBNPC1RAB9ACHRM1DDAH1 | |
| SCHEMBL7854448 | 0.80 | POLB (0.92) | POLBNPC1RAB9ACHRM1DDAH1 | |
| SCHEMBL7006523 | 0.80 | POLB (1.00) | POLBNPC1RAB9ACHRM1DDAH1 | |
| SCHEMBL9113349 | 0.79 | POLB (0.60) | POLBNPC1RAB9ACHRM1DDAH1 | |
| SCHEMBL7854826 | 0.78 | POLB (0.96) | POLBNPC1RAB9ACHRM1DDAH1 | |
| SCHEMBL7856315 | 0.78 | POLB (0.96) | POLBNPC1RAB9ACHRM1DDAH1 | |
| SCHEMBL7856311 | 0.78 | POLB (0.96) | POLBNPC1RAB9ACHRM1DDAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |