Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 3/20 | 0.66 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.66 |
| ▸ | CCR3 | P51677 | 2/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14307260 | 0.79 | CCR3 (0.69) | OPRL1OPRM1CCR3DRD2ADRA1A | |
| SCHEMBL9676304 | 0.78 | SIGMAR1 (0.85) | SIGMAR1 | |
| SCHEMBL9533670 | 0.77 | DRD2 (0.60) | OPRL1OPRM1CCR3DRD2ADRA1A | |
| SCHEMBL10287975 | 0.76 | CCR3 (0.65) | OPRL1OPRM1CCR3DRD2ADRA1A | |
| SCHEMBL14282299 | 0.75 | DRD2 (0.71) | OPRL1OPRM1CCR3DRD2ADRA1A | |
| SCHEMBL10287607 | 0.75 | OPRM1 (0.63) | OPRL1OPRM1CCR3DRD2ADRA1A | |
| SCHEMBL9676151 | 0.75 | SIGMAR1 (0.77) | SIGMAR1 | |
| SCHEMBL14282287 | 0.74 | CCR3 (0.61) | OPRL1OPRM1CCR3SIGMAR1DRD2 | |
| SCHEMBL9677462 | 0.73 | SIGMAR1 (0.77) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9455133 | 0.73 | SIGMAR1 (0.58) | OPRL1OPRM1CCR3SIGMAR1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0541802-B1 | DIPHENYLMETHYLPIPERAZINE DERIVATIVE | KANEKO NOBORU (JP) | 1994-10-12 | — | — | EP | disclosed |
| US-5304558-A | Diphenylmethyl piperazine derivatives | KIRIN BREWERY CO., LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| EP-0541802-A1 | DIPHENYLMETHYLPIPERAZINE DERIVATIVE | KANEKO, Noboru (JP) | 1993-05-19 | — | — | EP | disclosed |