Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.56 |
| ▸ | CCR3 | P51677 | 2/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | DRD1 | P21728 | 2/20 | 0.52 |
| ▸ | DRD5 | P21918 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | HTR7 | P34969 | 2/20 | 0.52 |
| ▸ | HRH1 | P35367 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | HTR2B | P41595 | 2/20 | 0.52 |
| ▸ | CCR1 | P32246 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529535 | 0.86 | DRD2 (0.60) | DRD2OPRM1ADRA1AHTR1ADRD1 | |
| SCHEMBL9529336 | 0.86 | OPRL1 (0.57) | DRD2OPRM1OPRL1CCR3CCR1 | |
| SCHEMBL14307260 | 0.83 | CCR3 (0.69) | DRD2OPRM1OPRL1CCR3ADRA1A | |
| SCHEMBL8741960 | 0.81 | OPRL1 (0.55) | DRD2OPRM1OPRL1CCR3 | |
| SCHEMBL10287607 | 0.79 | OPRM1 (0.63) | DRD2OPRM1OPRL1CCR3ADRA1A | |
| SCHEMBL9302682 | 0.77 | OPRL1 (0.66) | DRD2OPRM1OPRL1CCR3ADRA1A | |
| SCHEMBL1132636 | 0.75 | CCR1 (0.65) | DRD2CCR3ADRA1AHTR1ADRD1 | |
| SCHEMBL11938907 | 0.75 | DRD2 (0.65) | DRD2CCR3ADRA1AHTR1ADRD1 | |
| SCHEMBL10610496 | 0.75 | DRD2 (0.65) | DRD2CCR3ADRA1AHTR1ADRD1 | |
| SCHEMBL7236512 | 0.74 | CCR1 (0.62) | DRD2OPRM1OPRL1CCR3ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556342-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYOGYSZERKUTATO INTEZET K.V. (HU) | 1993-08-25 | — | — | EP | disclosed |
| WO-1992007854-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYÓGYSZERKUTATÓ INTÉZET KV. (HU) | 1992-05-14 | — | — | WO | disclosed |