Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CRHBP | P24387 | 2/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.34 |
| ▸ | BRS3 | P32247 | 3/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 2/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302701 | 0.77 | BRS3 (0.45) | AGTR1AGTR2BRS3 | |
| SCHEMBL9304405 | 0.77 | AGTR1 (0.42) | AGTR1AGTR2BRS3 | |
| SCHEMBL9303359 | 0.75 | HPGD (0.39) | ALDH1A1TDP1AGTR1AGTR2KDM4E | |
| SCHEMBL5592930 | 0.74 | BRS3 (0.39) | ALDH1A1TDP1KDM4EHPGDCRHBP | |
| SCHEMBL9302495 | 0.74 | AGTR1 (0.37) | AGTR1AGTR2BRS3 | |
| SCHEMBL9303312 | 0.74 | BRS3 (0.38) | AGTR1AGTR2BRS3TLR7 | |
| SCHEMBL9302908 | 0.74 | AGTR1 (0.37) | ALDH1A1AGTR1AGTR2KDM4EBRS3 | |
| SCHEMBL7014285 | 0.73 | TLR7 (0.45) | AGTR1AGTR2TLR7 | |
| SCHEMBL9303418 | 0.69 | AGTR1 (0.34) | AGTR1AGTR2 | |
| SCHEMBL8476707 | 0.69 | KDM4E (0.41) | ALDH1A1TDP1KDM4EHPGDBRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354766-A | 2-Ethoxy-1-((2'(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl) biphenyl-4-yl)methyl)benzimidazole-7-carboxylic acid; hypotensive agents; CNS activity | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-10-11 | — | — | US | disclosed |