Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 2/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302701 | 0.89 | BRS3 (0.45) | BRS3AGTR1AGTR2BDKRB1ACHE | |
| SCHEMBL9302908 | 0.83 | AGTR1 (0.37) | BRS3AGTR1AGTR2BDKRB1 | |
| SCHEMBL9304405 | 0.81 | AGTR1 (0.42) | BRS3AGTR1AGTR2BDKRB1ACHE | |
| SCHEMBL9302495 | 0.79 | AGTR1 (0.37) | BRS3AGTR1AGTR2 | |
| SCHEMBL9302784 | 0.74 | ALDH1A1 (0.35) | BRS3AGTR1AGTR2TLR7 | |
| SCHEMBL9303418 | 0.73 | AGTR1 (0.34) | AGTR1AGTR2ACHE | |
| SCHEMBL9044849 | 0.72 | BRS3 (0.45) | BRS3AGTR1AGTR2BDKRB1ACHE | |
| SCHEMBL8357009 | 0.72 | TLR7 (0.39) | AGTR1AGTR2CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL7019058 | 0.71 | AGTR2 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9303236 | 0.70 | BRS3 (0.35) | BRS3AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354766-A | 2-Ethoxy-1-((2'(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl) biphenyl-4-yl)methyl)benzimidazole-7-carboxylic acid; hypotensive agents; CNS activity | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-10-11 | — | — | US | disclosed |