Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.37 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
| ▸ | BRS3 | P32247 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303312 | 0.83 | BRS3 (0.38) | AGTR1AGTR2BDKRB1BRS3 | |
| SCHEMBL9302701 | 0.81 | BRS3 (0.45) | AGTR1AGTR2BDKRB1LTB4R2BRS3 | |
| SCHEMBL9304405 | 0.81 | AGTR1 (0.42) | AGTR1AGTR2BDKRB1LTB4R2BRS3 | |
| SCHEMBL9303418 | 0.80 | AGTR1 (0.34) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL9302495 | 0.79 | AGTR1 (0.37) | AGTR1AGTR2BRS3 | |
| SCHEMBL9302784 | 0.74 | ALDH1A1 (0.35) | AGTR1AGTR2KDM4EALDH1A1BRS3 | |
| SCHEMBL8364591 | 0.73 | KDM4E (0.40) | AGTR1AGTR2KDM4EALDH1A1 | |
| SCHEMBL7014979 | 0.72 | AGTR2 (0.52) | AGTR1AGTR2 | |
| SCHEMBL9303236 | 0.71 | BRS3 (0.35) | AGTR1AGTR2BRS3 | |
| SCHEMBL5592930 | 0.69 | BRS3 (0.39) | BDKRB1KDM4EALDH1A1LTB4R2BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354766-A | 2-Ethoxy-1-((2'(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl) biphenyl-4-yl)methyl)benzimidazole-7-carboxylic acid; hypotensive agents; CNS activity | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-10-11 | — | — | US | disclosed |