Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 15/20 | 0.53 |
| ▸ | PLG | P00747 | 10/20 | 0.51 |
| ▸ | F2 | P00734 | 10/20 | 0.51 |
| ▸ | PLAT | P00750 | 10/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 6/20 | 0.51 |
| ▸ | KLK1 | P06870 | 3/20 | 0.51 |
| ▸ | F10 | P00742 | 5/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304321 | 0.91 | PLAU (0.50) | PLAUPLGF2PLATPRSS1 | |
| SCHEMBL9303394 | 0.91 | PLAU (0.47) | PLAUPLGF2PLATPRSS1 | |
| SCHEMBL9302799 | 0.84 | RXFP1 (0.50) | PLAUPLGF2PLATKLK1 | |
| SCHEMBL9303301 | 0.82 | PTGES (0.49) | PLAUPLGF2PLATPRSS1 | |
| SCHEMBL9303759 | 0.81 | PLAU (0.50) | PLAUPLGF2PLATPRSS1 | |
| SCHEMBL9303405 | 0.81 | NPC1 (0.48) | PLAUPLGF2PLATKLK1 | |
| SCHEMBL9303344 | 0.80 | PLAU (0.74) | PLAUPLGF2PLATPRSS1 | |
| SCHEMBL9304281 | 0.80 | PLAU (0.61) | PLAUPLGF2PLATPRSS1 | |
| SCHEMBL9303028 | 0.80 | PLAU (0.63) | PLAUPLGF2PLATPRSS1 | |
| SCHEMBL9303131 | 0.80 | SIRT2 (0.46) | PLAUPLGF2PLATPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352704-A | Antiviral agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0434432-B1 | Guanidinobenzene derivatives | BANYU PHARMA CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0434432-A1 | Guanidinobenzene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |