Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28013355 | 0.87 | THRB (0.40) | THRBTSHRALDH1A1HIF1APOLB | |
| SCHEMBL8654494 | 0.82 | KMT2A (0.45) | ALDH1A1TP53POLBCYP1A2CYP2C9 | |
| SCHEMBL11608946 | 0.81 | POLB (0.42) | THRBTSHRALDH1A1POLBCYP1A2 | |
| SCHEMBL11607742 | 0.80 | THRB (0.58) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL7470086 | 0.79 | POLB (0.44) | THRBALDH1A1POLBCYP1A2CYP2C9 | |
| SCHEMBL8746171 | 0.78 | MEN1 (0.41) | ALDH1A1POLBHPGDCYP1A2CYP2C9 | |
| SCHEMBL3182778 | 0.78 | ALDH1A1 (0.42) | THRBTSHRALDH1A1TP53POLB | |
| SCHEMBL27738550 | 0.78 | POLB (0.43) | THRBALDH1A1POLBCYP1A2CYP2C9 | |
| SCHEMBL8746163 | 0.78 | CA2 (0.42) | ALDH1A1TP53POLBCYP1A2CYP2C9 | |
| SCHEMBL28516553 | 0.77 | POLB (0.40) | ALDH1A1POLBCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5284752-A | Methods of preparing a polymeric latex composition and water-insoluble biological reagent | EASTMAN KODAK COMPANY (US) | 1994-02-08 | — | — | US | disclosed |
| US-5234841-A | Methods of preparing a polymeric latex composition and water-insoluble biological reagent | EASTMAN KODAK COMPANY (US) | 1993-08-10 | — | — | US | disclosed |
| US-5149416-A | Water soluble, crosslinked acrylamide bases copolymer | EASTMAN KODAK COMPANY (US) | 1992-09-22 | — | — | US | disclosed |
| US-5073603-A | Acrylamide-based | EASTMAN KODAK COMPANY (US) | 1991-12-17 | — | — | US | disclosed |
| US-5053443-A | Methods of preparing a polymeric latex composition and water-insoluble biological reagent | EASTMAN KODAK COMPANY (US) | 1991-10-01 | — | — | US | disclosed |
| US-5043062-A | Particles with surface reactive groups linked to biological ligands | EASTMAN KODAK COMPANY (US) | 1991-08-27 | — | — | US | disclosed |
| US-4997772-A | Shell-core polymers | EASTMAN KODAK COMPANY (US) | 1991-03-05 | — | — | US | disclosed |