SCHEMBL3182778

SCHEMBL3182778

C=CC(=O)OCS(=O)(=O)c1ccccc1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
HTT P42858 2/20 0.42
ALOX12 P18054 1/20 0.42
THRB P10828 1/20 0.42
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
KEAP1 Q14145 1/20 0.37
NFE2L2 Q16236 1/20 0.37
POLB P06746 4/20 0.36
GAA P10253 3/20 0.36
CASP1 P29466 2/20 0.36
LMNA P02545 2/20 0.35
TSHR P16473 2/20 0.35
TP53 P04637 1/20 0.35
MAPT P10636 1/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
DHODH Q02127 1/20 0.35
ACHE P22303 1/20 0.35
CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5080070 0.84 THRB (0.41) ALDH1A1THRBKMT2APOLBGAA
SCHEMBL27778550 0.81 HTR6 (0.42) ALDH1A1HTTTHRBGAATSHR
SCHEMBL28013355 0.79 THRB (0.40) ALDH1A1HTTALOX12THRBMEN1
SCHEMBL9302812 0.78 THRB (0.49) ALDH1A1HTTALOX12THRBMEN1
SCHEMBL30055648 0.78 THRB (0.50) ALDH1A1HTTTHRBKMT2ALMNA
SCHEMBL9817862 0.77 TSHR (0.41) ALDH1A1HTTALOX12THRBKMT2A
SCHEMBL7470086 0.76 POLB (0.44) ALDH1A1HTTALOX12THRBMEN1
SCHEMBL27738550 0.75 POLB (0.43) ALDH1A1HTTALOX12THRBMEN1
SCHEMBL4595523 0.73 ALDH1A1 (0.42) ALDH1A1HTTALOX12THRBMEN1
SCHEMBL707747 0.72 ALDH1A1 (0.49) ALDH1A1HTTALOX12MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7662899-B2 Organic tellurium compound, process for producing the same, living radical polymerization initiator, process for producing polymer with the same, and polymer OTSUKA CHEMICAL CO., LTD. (JP) 2010-02-16 US disclosed
US-20080004366-A1 ORGANIC TELLURIUM COMPOUND, PROCESS FOR PRODUCING THE SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER WITH THE SAME, AND POLYMER YAMAGO SHIGERU 2008-01-03 US disclosed
US-7276569-B2 Organic tellurium compound, process for producing the same, living radical polymerization initiator, process for producing polymer with the same, and polymer OTSUKA CHEMICAL CO., LTD. (JP) 2007-10-02 US disclosed
US-20050245714-A1 Organic tellurium compound, process for producing the same, living radical polymerization initiator, process for producing polymer with the same, and polymer OTSUKA CHEMICAL CO., LTD. (JP) 2005-11-03 US disclosed
EP-1541550-A1 ORGANIC TELLURIUM COMPOUND, PROCESS FOR PRODUCING THE SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER WITH THE SAME, AND POLYMER Otsuka Chemical Co., Ltd. (JP) 2005-06-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050245714-A1 Organic tellurium compound, process for producing the same, living radical polymerization initiator, process for producing polymer with the same, and polymer ODC1, TERB1, TTI1 ALDH1A1 1201/4885HTT 1822/4885ALOX12 1685/4885
US-20080004366-A1 ORGANIC TELLURIUM COMPOUND, PROCESS FOR PRODUCING THE SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER WITH THE SAME, AND POLYMER ODC1, TERB1, TTI1 ALDH1A1 1201/4885HTT 1822/4885ALOX12 1685/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.