Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 7/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303150 | 0.83 | ADRA1D (0.59) | ADRA1DADRA1AADRA1BHTR1ASIGMAR1 | |
| SCHEMBL9301303 | 0.80 | ADRA1D (0.56) | ADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL17754013 | 0.77 | CXCR4 (0.56) | DRD2DRD4CXCR4ACHEBACE1 | |
| SCHEMBL9301871 | 0.72 | CXCR4 (0.61) | DRD2DRD4CXCR4ACHEBACE1 | |
| SCHEMBL9301121 | 0.72 | ACHE (0.45) | HTR1ASIGMAR1LTA4HDRD4CXCR4 | |
| SCHEMBL9303125 | 0.71 | ADRA1D (0.63) | ADRA1DADRA1AADRA1BHTR1ASIGMAR1 | |
| SCHEMBL13617921 | 0.71 | HTT (0.49) | HTR1ASIGMAR1ALDH1A1 | |
| SCHEMBL9302823 | 0.71 | ADRA1D (0.62) | ADRA1DADRA1AADRA1BHTR1ASIGMAR1 | |
| SCHEMBL19658389 | 0.71 | ACHE (0.58) | DRD2DRD4CXCR4ACHEALDH1A1 | |
| SCHEMBL9301600 | 0.71 | ADRA1D (0.74) | ADRA1DADRA1AADRA1BHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |