Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TAS2R14 | Q9NYV8 | 4/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302642 | 0.83 | ALDH1A1 (0.54) | MEN1KMT2APOLBHTR2C | |
| SCHEMBL9303789 | 0.81 | ESR1 (0.56) | CNR2MEN1KMT2AGAAL3MBTL1 | |
| SCHEMBL9302598 | 0.79 | NR1H3 (0.50) | MEN1KMT2APOLBHTR2C | |
| SCHEMBL9302028 | 0.77 | CA12 (0.52) | MEN1KMT2APOLBHTR2CTSHR | |
| SCHEMBL9594878 | 0.76 | CNR2 (0.72) | CNR2MEN1KMT2APOLBTAS2R14 | |
| SCHEMBL9302737 | 0.75 | CXCR4 (0.46) | MEN1KMT2APOLBHTR2CTSHR | |
| SCHEMBL9302302 | 0.75 | CXCR4 (0.48) | CNR2MEN1KMT2ATAS2R14TSHR | |
| SCHEMBL6804193 | 0.73 | CNR2 (0.85) | CNR2MEN1KMT2APOLBTAS2R14 | |
| SCHEMBL6797972 | 0.73 | CNR2 (0.79) | CNR2MEN1KMT2APOLBTAS2R14 | |
| SCHEMBL9303870 | 0.73 | CA2 (0.47) | CA12CA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | claimed |
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |