Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 4/20 | 0.38 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 4/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9305072 | 0.92 | CSNK2A2 (0.40) | TDP1MAOAMAOBACHECSNK2A2 | |
| SCHEMBL9302920 | 0.86 | TDP1 (0.41) | TDP1CAMK2DMAOAMAOBACHE | |
| SCHEMBL9304250 | 0.86 | TDP1 (0.41) | TDP1CAMK2DMAOAMAOBACHE | |
| SCHEMBL9304149 | 0.86 | TDP1 (0.41) | TDP1CAMK2DMAOAMAOBACHE | |
| Hydrochloric Acid SCHEMBL8142483 | 0.85 | TDP1 (0.42) | TDP1CAMK2DMAOAMAOBACHE | |
| SCHEMBL9303821 | 0.83 | PRKCB (0.40) | TDP1CAMK2DMERTK | |
| Hydrochloric Acid SCHEMBL8138785 | 0.83 | HSD17B10 (0.50) | TDP1CAMK2DMAOAMAOBACHE | |
| SCHEMBL9305694 | 0.82 | TDP1 (0.37) | TDP1CAMK2D | |
| SCHEMBL9304792 | 0.81 | MAPK13 (0.41) | TDP1CAMK2DMAOAMAOBACHE | |
| SCHEMBL8134219 | 0.79 | CDC7 (0.41) | TDP1MAOAMAOBACHEMERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296491-A | Pyrazolo[4,3-c]pyridines and their use as serotonin reuptake inhibitors | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-03-22 | — | — | US | claimed |