Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD40 | P25942 | 2/20 | 0.51 |
| ▸ | CD40LG | P29965 | 2/20 | 0.51 |
| ▸ | F2 | P00734 | 3/20 | 0.46 |
| ▸ | PLG | P00747 | 2/20 | 0.46 |
| ▸ | PLAU | P00749 | 2/20 | 0.46 |
| ▸ | PLAT | P00750 | 2/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.44 |
| ▸ | KLK1 | P06870 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303405 | 0.92 | NPC1 (0.48) | CD40CD40LGF2PLGPLAU | |
| SCHEMBL9302845 | 0.86 | PTGES (0.52) | F2PLGPLAUPLATNPC1 | |
| SCHEMBL9303615 | 0.83 | PDCD1 (0.55) | F2PLGPLAUPLATF10 | |
| SCHEMBL9303104 | 0.81 | NPC1 (0.49) | F10NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL9302652 | 0.81 | PLAU (0.48) | F2PLGPLAUPLATF10 | |
| SCHEMBL9303908 | 0.81 | PLG (0.48) | F2PLGPLAUPLATF10 | |
| SCHEMBL9303308 | 0.80 | PTGES (0.56) | NPC1RAB9ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9302612 | 0.79 | PLAU (0.55) | F2PLGPLAUPLATF10 | |
| SCHEMBL9303759 | 0.77 | PLAU (0.50) | F2PLGPLAUPLATF10 | |
| SCHEMBL9302624 | 0.77 | PLAU (0.53) | F2PLGPLAUPLATF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352704-A | Antiviral agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0434432-B1 | Guanidinobenzene derivatives | BANYU PHARMA CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0434432-A1 | Guanidinobenzene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |