Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.52 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303308 | 0.94 | PTGES (0.56) | PTGESCLK1SIRT2NPC1RAB9A | |
| SCHEMBL9303113 | 0.86 | CD40 (0.51) | SIRT2NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL9304048 | 0.85 | SIRT2 (0.55) | PTGESSIRT2KCNK3KCNK9MEN1 | |
| SCHEMBL9303515 | 0.82 | PTGES (0.48) | PTGESNPC1RAB9AMEN1KMT2A | |
| SCHEMBL9302930 | 0.82 | PTGES (0.51) | PTGESSIRT2NPC1RAB9ACYP1A2 | |
| SCHEMBL9304320 | 0.81 | PLAU (0.50) | PTGESSIRT2NPC1RAB9AKCNK3 | |
| SCHEMBL9303405 | 0.81 | NPC1 (0.48) | SIRT2NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL7501198 | 0.80 | PKM (0.48) | PTGESCLK1NPC1RAB9ACYP1A2 | |
| SCHEMBL9302840 | 0.80 | PTGES (0.51) | PTGESSIRT2NPC1RAB9AKCNK3 | |
| SCHEMBL9304163 | 0.80 | PTGES (0.54) | PTGESNPC1RAB9ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352704-A | Antiviral agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0434432-B1 | Guanidinobenzene derivatives | BANYU PHARMA CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0434432-A1 | Guanidinobenzene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |