Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.56 |
| ▸ | CLK1 | P49759 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PLK4 | O00444 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302845 | 0.94 | PTGES (0.52) | PTGESCLK1SIRT2NPC1RAB9A | |
| SCHEMBL9304048 | 0.88 | SIRT2 (0.55) | PTGESSIRT2MEN1KMT2APKM | |
| SCHEMBL9303405 | 0.87 | NPC1 (0.48) | SIRT2NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL9303936 | 0.84 | PTGES (0.52) | PTGESSIRT2NPC1RAB9ACYP1A2 | |
| SCHEMBL9304321 | 0.82 | PLAU (0.50) | PTGESSIRT2NPC1RAB9AMEN1 | |
| SCHEMBL9303301 | 0.81 | PTGES (0.49) | PTGESSIRT2NPC1RAB9AMEN1 | |
| SCHEMBL9303249 | 0.81 | PLAU (0.60) | PTGES | |
| SCHEMBL9305495 | 0.81 | PLAU (0.54) | PTGESNPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL9303445 | 0.80 | NPC1 (0.54) | NPC1RAB9ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9304320 | 0.80 | PLAU (0.50) | PTGESSIRT2NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352704-A | Antiviral agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0434432-B1 | Guanidinobenzene derivatives | BANYU PHARMA CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0434432-A1 | Guanidinobenzene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |