Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 9/20 | 0.50 |
| ▸ | PLG | P00747 | 7/20 | 0.50 |
| ▸ | PLAT | P00750 | 6/20 | 0.50 |
| ▸ | F2 | P00734 | 5/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.50 |
| ▸ | KLK1 | P06870 | 3/20 | 0.50 |
| ▸ | F10 | P00742 | 2/20 | 0.50 |
| ▸ | NQO2 | P16083 | 1/20 | 0.50 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302840 | 0.88 | PTGES (0.51) | PLAUPLGPLATF2KLKB1 | |
| SCHEMBL9303394 | 0.88 | PLAU (0.47) | PLAUPLGPLATF2KLKB1 | |
| SCHEMBL9302832 | 0.82 | RXFP1 (0.50) | PLAUPLGPLATF2F10 | |
| SCHEMBL9303908 | 0.81 | PLG (0.48) | PLAUPLGPLATF2KLKB1 | |
| SCHEMBL9303115 | 0.81 | PLAU (0.53) | PLAUPLGPLATF2KLKB1 | |
| SCHEMBL9302624 | 0.80 | PLAU (0.53) | PLAUPLGPLATF2KLKB1 | |
| SCHEMBL9302612 | 0.80 | PLAU (0.55) | PLAUPLGPLATF2KLKB1 | |
| SCHEMBL9303301 | 0.79 | PTGES (0.49) | PLAUPLGPLATF2KLKB1 | |
| Hydrochloric Acid SCHEMBL6777262 | 0.79 | NR4A1 (0.49) | NQO2MEN1KMT2A | |
| SCHEMBL4063687 | 0.78 | PTPN1 (0.66) | PLAUPLGPLATF2KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352704-A | Antiviral agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0434432-B1 | Guanidinobenzene derivatives | BANYU PHARMA CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0434432-A1 | Guanidinobenzene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |