Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALPL | P05186 | 2/20 | 0.45 |
| ▸ | ALPI | P09923 | 2/20 | 0.45 |
| ▸ | ALPG | P10696 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL244446 | 0.98 | ALOX15 (0.52) | ALOX15CYP2C9CYP2C19CYP1A2KMT2A | |
| SCHEMBL9785295 | 0.85 | MAPT (0.49) | KMT2AMEN1ALPLNPC1ALDH1A1 | |
| SCHEMBL11822210 | 0.84 | PLA2G4B (0.55) | CYP1A2KMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL11821617 | 0.83 | LMNA (0.60) | CYP2C19CYP1A2KMT2AMEN1NPC1 | |
| SCHEMBL16383050 | 0.83 | ALOX15 (0.57) | ALOX15CYP2C9CYP2C19CYP1A2KMT2A | |
| SCHEMBL16601102 | 0.83 | ALOX15 (0.49) | ALOX15CYP2C9CYP2C19CYP1A2KMT2A | |
| SCHEMBL9785247 | 0.83 | L3MBTL1 (0.51) | CYP2C19CYP1A2KMT2AMEN1NPC1 | |
| SCHEMBL9466281 | 0.83 | GAA (0.49) | ALOX15KMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL11825441 | 0.82 | LMNA (0.48) | CYP2C19CYP1A2KMT2ANPC1ALDH1A1 | |
| SCHEMBL11822203 | 0.82 | HSD17B10 (0.53) | CYP2C19KMT2AMEN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5376683-A | Δ8- and Δ9-prostaglandin derivatives, process for their production and their pharmaceutical use | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-12-27 | — | — | US | disclosed |
| US-5235072-A | 2-OXABICYCLO(2,2,1)HEPTANE DERIVATIVES AND PHARMACEUTICAL | SCHERING AKTIENGSELLSCHAFT (DE) | 1993-08-10 | — | — | US | disclosed |