Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 8/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KLK1 | P06870 | 7/20 | 0.46 |
| ▸ | PLG | P00747 | 6/20 | 0.46 |
| ▸ | F2 | P00734 | 5/20 | 0.46 |
| ▸ | PLAT | P00750 | 5/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.43 |
| ▸ | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | P62805 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303518 | 0.92 | NPC1 (0.49) | PLAUNPC1RAB9AKLK1PLG | |
| SCHEMBL9303274 | 0.83 | PLAU (0.62) | PLAUNPC1RAB9AKLK1PLG | |
| SCHEMBL9303439 | 0.83 | NPC1 (0.45) | PLAUNPC1RAB9AKLK1PLG | |
| SCHEMBL9303554 | 0.82 | NPC1 (0.46) | PLAUNPC1RAB9ACHRNB2CHRNB4 | |
| SCHEMBL9303484 | 0.82 | NPC1 (0.49) | PLAUNPC1RAB9AHSD17B10CHRNB2 | |
| SCHEMBL9303517 | 0.81 | PLAU (0.58) | PLAUNPC1RAB9AKLK1PLG | |
| SCHEMBL9304170 | 0.81 | PLAU (0.54) | PLAUNPC1RAB9AKLK1PLG | |
| SCHEMBL9303327 | 0.80 | RAB9A (0.44) | PLAUNPC1RAB9AH4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16EP300 | |
| SCHEMBL7335597 | 0.80 | PLAU (0.74) | PLAUNPC1RAB9AKLK1PLG | |
| SCHEMBL9303218 | 0.80 | PLAU (0.44) | PLAUNPC1RAB9AKLK1PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352704-A | Antiviral agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0434432-B1 | Guanidinobenzene derivatives | BANYU PHARMA CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0434432-A1 | Guanidinobenzene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |