Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 2/20 | 0.76 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302693 | 0.90 | PTAFR (0.80) | PTAFRDCTPP1PTGDR2ALDH1A1GAA | |
| SCHEMBL9302507 | 0.88 | PTAFR (0.77) | PTAFRPTGDR2KCNH2ALDH1A1GAA | |
| SCHEMBL9303630 | 0.88 | PTAFR (0.77) | PTAFRPTGDR2ALDH1A1GAALMNA | |
| SCHEMBL9302834 | 0.87 | PTAFR (1.00) | PTAFRPTGDR2KCNH2ALDH1A1GAA | |
| SCHEMBL9302097 | 0.85 | PTAFR (0.72) | PTAFRPTGDR2ALDH1A1GAALMNA | |
| SCHEMBL9302509 | 0.77 | PTAFR (0.83) | PTAFRKCNH2 | |
| SCHEMBL9301338 | 0.75 | PTAFR (0.78) | PTAFRPTGDR2ALDH1A1GAALMNA | |
| SCHEMBL9304261 | 0.73 | PTAFR (0.75) | PTAFRPTGDR2KCNH2ALDH1A1GAA | |
| SCHEMBL10474862 | 0.72 | PTAFR (0.50) | PTAFRPTGDR2ALDH1A1GAALMNA | |
| SCHEMBL13508761 | 0.72 | DCTPP1 (0.74) | DCTPP1KCNH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | claimed |
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |