Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 2/20 | 0.75 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | HRH1 | P35367 | 3/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302834 | 0.86 | PTAFR (1.00) | PTAFRHRH3KDM4EALDH1A1MEN1 | |
| SCHEMBL9301338 | 0.82 | PTAFR (0.78) | PTAFRKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9302509 | 0.77 | PTAFR (0.83) | PTAFRHRH3CYP2D6HRH1CHRM1 | |
| SCHEMBL9302693 | 0.76 | PTAFR (0.80) | PTAFRHRH3KDM4EALDH1A1MEN1 | |
| SCHEMBL27767911 | 0.75 | CTSD (0.60) | HRH3KDM4EALDH1A1HPGDHTT | |
| SCHEMBL230485 | 0.74 | ALDH1A1 (0.66) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL29411979 | 0.74 | ALDH1A1 (0.66) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL9303630 | 0.74 | PTAFR (0.77) | PTAFRKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9302507 | 0.74 | PTAFR (0.77) | PTAFRHRH3KDM4EALDH1A1MEN1 | |
| SCHEMBL9303479 | 0.73 | PTAFR (0.76) | PTAFRKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | claimed |
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |