Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 2/20 | 0.77 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | LSS | P48449 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302507 | 0.92 | PTAFR (0.77) | PTAFRCNR2PTGDR2LSSGAA | |
| SCHEMBL9303479 | 0.88 | PTAFR (0.76) | PTAFRCNR2PTGDR2LSSGAA | |
| SCHEMBL9302834 | 0.87 | PTAFR (1.00) | PTAFRPTGDR2GAAALDH1A1LMNA | |
| SCHEMBL9302097 | 0.87 | PTAFR (0.72) | PTAFRCNR2PTGDR2GAAL3MBTL1 | |
| SCHEMBL9302693 | 0.86 | PTAFR (0.80) | PTAFRCNR2PTGDR2GAAL3MBTL1 | |
| SCHEMBL9302509 | 0.78 | PTAFR (0.83) | PTAFRGALR3NR2F2RAB9A | |
| SCHEMBL9301338 | 0.75 | PTAFR (0.78) | PTAFRPTGDR2GAAHTR2AHTR2C | |
| SCHEMBL9304261 | 0.74 | PTAFR (0.75) | PTAFRPTGDR2GAAL3MBTL1ALDH1A1 | |
| SCHEMBL12771510 | 0.71 | TNF (0.69) | GAAALDH1A1GALR3NR2F2RAB9A | |
| SCHEMBL9302294 | 0.70 | GALR3 (0.67) | PTAFRALDH1A1GALR3NR2F2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | claimed |
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |