Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303397 | 0.96 | KMT2A (0.47) | THRBKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL8913713 | 0.91 | KMT2A (0.49) | THRBKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL9303442 | 0.91 | KMT2A (0.49) | THRBKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL8911968 | 0.87 | THRB (0.60) | THRBKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL9304788 | 0.87 | MAPT (0.52) | THRBKMT2ASMN1; SMN2MAPTCYP2C9 | |
| SCHEMBL8913231 | 0.87 | THRB (0.57) | THRBKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL9302777 | 0.85 | GPR52 (0.45) | THRBKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL10798412 | 0.84 | THRB (0.64) | THRBKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL10799184 | 0.84 | THRB (0.64) | THRBKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL8915970 | 0.84 | F2 (0.48) | THRBSMN1; SMN2MAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304667-A | Cyclosiloxanes containing mesogenic side groups | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1994-04-19 | — | — | US | disclosed |
| US-5221759-A | CYCLOSILOXANES CONTAINING MESOGENIC SIDE GROUPS | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1993-06-22 | — | — | US | disclosed |