Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 5/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303618 | 0.96 | GPR52 (0.46) | GPR52THRBMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8912455 | 0.91 | PARP10 (0.50) | GPR52THRBMAPTALDH1A1L3MBTL1 | |
| SCHEMBL9305285 | 0.91 | PARP10 (0.50) | GPR52THRBMAPTALDH1A1L3MBTL1 | |
| SCHEMBL18540255 | 0.85 | THRB (0.45) | GPR52THRBMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL18540085 | 0.85 | THRB (0.52) | THRBMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL8913231 | 0.85 | THRB (0.57) | THRBMAPTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL9304788 | 0.85 | MAPT (0.52) | GPR52THRBMAPTSMN1; SMN2KMT2A | |
| SCHEMBL8911968 | 0.85 | THRB (0.60) | THRBMAPTSMN1; SMN2KMT2ATDP1 | |
| SCHEMBL18777290 | 0.85 | ALDH1A1 (0.63) | MAPTALDH1A1L3MBTL1PARP10HDAC2 | |
| SCHEMBL9303608 | 0.85 | THRB (0.47) | THRBMAPTSMN1; SMN2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304667-A | Cyclosiloxanes containing mesogenic side groups | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1994-04-19 | — | — | US | disclosed |
| US-5221759-A | CYCLOSILOXANES CONTAINING MESOGENIC SIDE GROUPS | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1993-06-22 | — | — | US | disclosed |