Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | CCND2 | P30279 | 1/20 | 0.36 |
| ▸ | CCND3 | P30281 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 3/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302582 | 0.93 | ALDH1A1 (0.37) | CDK4CCND1CCND2CCND3HRH3 | |
| SCHEMBL9303155 | 0.87 | HRH3 (0.38) | CDK4CCND1CCND2CCND3HRH3 | |
| SCHEMBL9302286 | 0.85 | OPRM1 (0.38) | CDK4CCND1CCND2CCND3HRH3 | |
| SCHEMBL9301295 | 0.83 | OPRM1 (0.36) | CDK4CCND1CCND2CCND3HRH3 | |
| SCHEMBL9301342 | 0.81 | STS (0.38) | HRH3OPRM1OPRD1OGFRL1STS | |
| SCHEMBL9304073 | 0.80 | MAPT (0.39) | HRH3OPRM1OPRD1OGFRL1ALDH1A1 | |
| SCHEMBL9303642 | 0.79 | OPRM1 (0.36) | CDK4CCND1CCND2CCND3HRH3 | |
| SCHEMBL9302223 | 0.74 | KDM4E (0.41) | ALDH1A1KDM4EPIK3CAMAPTLMNA | |
| SCHEMBL9301409 | 0.73 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTTP53LMNA | |
| SCHEMBL9847726 | 0.73 | KDM4E (0.40) | ALDH1A1KDM4EPIK3CAMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0501578-A1 | Pyranylphenyl hydroxyalkylnaphthoic acids as inhibitors of leukotriene biosynthesis | MERCK FROSST CANADA INC. (CA) | 1992-09-02 | — | — | EP | claimed |
| US-5281720-A | Antiasthmatics, antiallergens, antiinflammatory agents and cytoprotective agents | MERCK FROSST CANADA, INC. | 1994-01-25 | — | — | US | disclosed |
| EP-0501578-A1 | Pyranylphenyl hydroxyalkylnaphthoic acids as inhibitors of leukotriene biosynthesis | MERCK FROSST CANADA INC. (CA) | 1992-09-02 | — | — | EP | disclosed |