Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302040 | 0.87 | KDM4E (0.41) | MAPTKDM4EALDH1A1TSHRPOLB | |
| SCHEMBL9302272 | 0.84 | MAPT (0.42) | MAPTKDM4ETHRBGPR119ALDH1A1 | |
| SCHEMBL9303155 | 0.84 | HRH3 (0.38) | MAPTKDM4ETHRBHRH3GPR119 | |
| SCHEMBL9302286 | 0.81 | OPRM1 (0.38) | MAPTKDM4ETHRBHRH3GPR119 | |
| SCHEMBL9301516 | 0.81 | CASP3 (0.34) | HRH3OPRM1OPRD1OGFRL1ALDH1A1 | |
| SCHEMBL9301445 | 0.80 | ALDH1A1 (0.44) | MAPTKDM4EALDH1A1TSHRGAA | |
| SCHEMBL9303636 | 0.80 | CDK4 (0.36) | MAPTKDM4ETHRBHRH3GPR119 | |
| SCHEMBL9302582 | 0.80 | ALDH1A1 (0.37) | MAPTKDM4ETHRBHRH3GPR119 | |
| Trifluoroacetic Acid SCHEMBL9301612 | 0.80 | KDM4E (0.46) | MAPTKDM4EALDH1A1TSHRGAA | |
| SCHEMBL9301295 | 0.79 | OPRM1 (0.36) | MAPTKDM4ETHRBHRH3GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5283248-A | Bactericides, enzyme inhibitor of DNA-gyrase in bacteria | HOFFMANN-LA ROCHE INC. (US) | 1994-02-01 | — | — | US | disclosed |