Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | LARS1 | Q9P2J5 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302410 | 0.85 | LMNA (0.56) | SMN1; SMN2MAPTHTTLMNAALDH1A1 | |
| SCHEMBL9301975 | 0.81 | CYP19A1 (0.54) | CYP19A1 | |
| SCHEMBL28195553 | 0.81 | HTT (0.75) | SMN1; SMN2MAPTHTTLMNAALDH1A1 | |
| SCHEMBL9304262 | 0.81 | ALDH1A1 (0.54) | LMNAALDH1A1MAPK1CYP19A1 | |
| SCHEMBL9302429 | 0.78 | TP53 (0.45) | SMN1; SMN2MAPTHTTLMNAALDH1A1 | |
| SCHEMBL28003775 | 0.77 | SMN1; SMN2 (0.74) | SMN1; SMN2MAPTHTTLMNAALDH1A1 | |
| SCHEMBL9302327 | 0.76 | POLB (0.56) | MAPTHTTLMNAALDH1A1MAPK1 | |
| SCHEMBL7415584 | 0.73 | SMN1; SMN2 (0.78) | SMN1; SMN2MAPTHTTLMNAALDH1A1 | |
| SCHEMBL9302813 | 0.73 | ALDH1A1 (0.48) | SMN1; SMN2HTTLMNAALDH1A1PKM | |
| SCHEMBL30596341 | 0.72 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPTHTTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | claimed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | claimed |
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |