Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 5/20 | 0.46 |
| ▸ | F2 | P00734 | 4/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.46 |
| ▸ | PLG | P00747 | 3/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.46 |
| ▸ | PLAT | P00750 | 2/20 | 0.46 |
| ▸ | KLK1 | P06870 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | PLK4 | O00444 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303394 | 0.91 | PLAU (0.47) | PLAUF2PRSS1PLGKLKB1 | |
| SCHEMBL9304321 | 0.91 | PLAU (0.50) | PTGESPLAUF2PRSS1PLG | |
| SCHEMBL9302840 | 0.89 | PTGES (0.51) | PTGESPLAUF2PRSS1PLG | |
| SCHEMBL9303292 | 0.83 | RXFP1 (0.52) | PTGESPLAUF2PLGPLAT | |
| SCHEMBL9303115 | 0.82 | PLAU (0.53) | PLAUF2PRSS1PLGKLKB1 | |
| SCHEMBL9303308 | 0.81 | PTGES (0.56) | PTGESSIRT2NPC1RAB9AKMT2A | |
| SCHEMBL9303041 | 0.81 | PLAU (0.61) | PLAUF2PRSS1PLGKLKB1 | |
| SCHEMBL9305779 | 0.81 | PLAU (0.71) | PLAUF2PRSS1PLGKLKB1 | |
| SCHEMBL9303936 | 0.81 | PTGES (0.52) | PTGESPLAUF2PRSS1PLG | |
| SCHEMBL9303751 | 0.80 | ITGB3 (0.62) | PLAUF2PRSS1PLGKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352704-A | Antiviral agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0434432-B1 | Guanidinobenzene derivatives | BANYU PHARMA CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0434432-A1 | Guanidinobenzene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |