Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 2/20 | 0.56 |
| ▸ | HTR5A | P47898 | 2/20 | 0.56 |
| ▸ | NCF1 | P14598 | 2/20 | 0.56 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.56 |
| ▸ | HTR3B | O95264 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | HTR1D | P28221 | 1/20 | 0.56 |
| ▸ | HTR1B | P28222 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.56 |
| ▸ | MTOR | P42345 | 1/20 | 0.56 |
| ▸ | HTR3A | P46098 | 1/20 | 0.56 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.56 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30725496 | 1.00 | HTR2C (0.56) | HTR2CHTR6HTR5ANCF1HTR3E | |
| Ethoxycarbonyl Group SCHEMBL29174573 | 0.83 | HTR2C (0.42) | HTR2CHTR6HTR5ANCF1HTR3E | |
| SCHEMBL15971599 | 0.81 | KDM4E (0.53) | NCF1HSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL3600354 | 0.81 | DRD2 (0.49) | HTR2CHTR6HTR1AHTR1DHTR1B | |
| SCHEMBL15971628 | 0.79 | LMNA (0.42) | HTR2CTSHRHSD17B10KDM4EALDH1A1 | |
| SCHEMBL3560946 | 0.78 | HTR6 (0.53) | HTR6HTR5ANCF1HTR3EHTR3B | |
| SCHEMBL22721093 | 0.76 | BPTF (0.44) | HTR2C | |
| SCHEMBL15971862 | 0.75 | LMNA (0.43) | HTR6CYP1A2HTR1AHTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL22720936 | 0.75 | BPTF (0.42) | HTR2C | |
| SCHEMBL2545146 | 0.73 | HTR3E (0.56) | HTR6HTR5ANCF1HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332732-A | Thiophene and pyridine antipsychotic agents | MCNEILAB, INC. (US) | 1994-07-26 | — | — | US | disclosed |