SCHEMBL9303868

SCHEMBL9303868

C1=CC[Si](c2ccccc2)(c2ccccc2)C1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MGLL Q99685 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15637376 0.75 MAPT (0.35) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL7715185 0.75 MAPT (0.35) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL9306680 0.72 LMNA (0.30)
SCHEMBL18131846 0.72
SCHEMBL3798583 0.71 MAPT (0.32) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL8914562 0.71 MAPT (0.32) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL3898942 0.69 MAPT (0.30) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL9637410 0.69 TSHR (0.35) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL8427727 0.69 MEN1 (0.32) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL20087445 0.69 MAPT (0.30) MAPTHPGDSMN1; SMN2MGLLHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5300605-A Cross-linkable poly(unsaturated carbosilane) homopolymers and copolymers and method of making same UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1994-04-05 US disclosed
US-5260377-A Crosslinkable carbosilane polymer formulations UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1993-11-09 US disclosed
WO-1993017063-A1 CROSSLINKABLE CARBOSILANE POLYMER FORMULATIONS UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1993-09-02 WO disclosed
US-5171810-A CROSSLINKABLE POLY(UNSATURATED CARBOSILANE) COPOLYMERS AND METHODS OF MAKING SAME UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1992-12-15 US disclosed
US-5171792-A Crosslinkable saturated and unsaturated carbosilane polymers and formulations UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1992-12-15 US disclosed
US-5169916-A Crosslinkable poly(unsaturated carbosilane) polymers and methods of making same UNIVERSITY OF SOUTH CALIFORNIA (US) 1992-12-08 US disclosed
US-5130390-A Crosslinkable saturated and unsaturated carbosilane polymers and formulations UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1992-07-14 US disclosed